Evolution of Explanatory Models of Periodontal Disease Pathogenesis

https://doi.org/10.25100/re.v17i2.5700
periodontitis etiopathogenesis immunoinflammatory response biofilm gingival interface genetic expression

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Published: Jul 15, 2009
Issue: Vol. 17 No. 2 (2009)
Section Case Series

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Authors

Ana Isabel Restrepo Universidad del Valle. Cali, Colombia.
Solange Velasco Universidad del Valle. Cali, Colombia.
Leonardo Franco Universidad del Valle. Cali, Colombia.
Abstract

Summary: This review analyze
various periodontal disease pathogenesis models. The biological models that explain the pathogenesis
of the periodontal disease have presented an evolutionary change from 1960, when it was assumed that
only bacterial deposits caused the disease to nowdays. It is recently accepted that periodontal
disease is an infection that challenges the immune system and generates an inflammatory response
that affects the homeostasis of the periodontium. Additional factors like environment, genetics and
acquired factors also interact with the microbial milieu and the immune response to influence
disease progression. Key words: Periodontitis. Etiopathogenesis. Immunoinflamatory response. Biofilm
gingival interface. Genetic expression.

Author Biographies

Ana Isabel Restrepo, Universidad del Valle. Cali, Colombia.

Estudiante Postgrado de Periodoncia, Escuela de Odontología.

Leonardo Franco, Universidad del Valle. Cali, Colombia.

Estudiante Postgrado de Ortodoncia, Escuela de Odontología.

How to Cite
Restrepo, A. I., Velasco, S., & Franco, L. (2009). Evolution of Explanatory Models of Periodontal Disease Pathogenesis. Revista Estomatología, 17(2). https://doi.org/10.25100/re.v17i2.5700
References
Ko r nma n KS . Ma p p i n g t h e
pathogenesis of periodontitis: a
new look. J Periodontol 2008;79(8
Suppl):1560-8.
2. Page RC, Schroeder HE. Pathogenesis
of inflammatory periodontal disease.
A summary of current work. Lab
Invest 1976;34(3):235-49.
3. Kornman KS, Page RC, Tonetti MS.
The host response to the microbial
challenge in periodontitis: assembling
the players. Periodontol 2000
1997;14:33-53.
4. Kornman KS, Crane A, Wang HY, di
Giovine FS, Newman MG, Pirk FW,
Wilson TG Jr, Higginbottom FL, Duff
GW. The interleukin-1 genotype as a
severity factor in adult periodontal
disease. J Clin Periodontol 1997
;24(1):72-7.
5. Offenbacher S, Barros SP, Singer
RE, Moss K, Williams RC, Beck JD.
Periodontal disease at the biofilmgingival
interface. J Periodontol
2007;78(10):1911-25.
6. Oringer RJ; Research, Science, and
Therapy Committee of the American
Ac ademy of Pe r iodontology.
Modulation of the host response in
periodontal therapy. J Periodontol
2002;73(4):460-70.
7. J e ff coa t MK. Sa f e ty of or a l
bisphosphonates: controlled studies
on alveolar bone. Int J Oral Maxillofac
Implants 2006;21(3):349-53.

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