Profilaxis antibiótica en cirugía de terceros molares incluidos

Abstract

The purpose of this study was to investigate if antibiotic prevention in surgery of third molars included is effective for the control of postsurgery infection. In the literature, there are a great variety of opinions about the use of antibiotics. In this study, the selected antibiotic was amoxacilina 1 gr. orally given one hour before the procedure and six hours later. There were two groups of patients, one of those which received the antibiotic and the other the placebo. Conventional protocols were used for the asepsis, antisepsis and sterilization of the instrumental, likewise for the surgical procedure made by a maxillofacial surgeon. Selected patients were classified ASA I (American Association of anaesthesiology) that don't have any infectious process in oral cavity and acceptable oral hygiene. The study design was a triple blind controlled where the surgeon, the patient or the statisticon knew wich medication was given to the patient. AlI the patients were controlled to the fifth and tenth day possurgery. Patients were instructed to inform the doctor arised any complication immediately. In the event ofbeing presented an infection, it was recomended cultivation and antibiogram for aerobic and anaerobic and while the results are received treatment with clindamicina. The investigation was approved by the ethics comrnittee in human health at the University ofValley and all the patients filled a consent formato 102 patients were studied (49 received antibiotic and 53 p1acebo) in a period from September 1, 1.998 to September 1, 2.000. No patient resulted infected. The conclusion of the investigation therefore was that the use of antibiotics is not required for the surgery of third included molars.