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Introduction: Type IV Bacterial Secretion Systems (TFSS) have a variety of biological functions such as the exchange of genetic material with other bacteria and virulent translocation of DNA with its effector proteins into host cells. A. baumannii is a pathogen that causes infections in humans and exhibits high rates of multidrug resistance to drugs.


Objective: To relate how type IV secretion systems is associated with patterns of resistance and virulence in A. baumannii.


Materials and Methods: Exhaustive search in PMC (NCBI) using a set of keywords was performed. Results: The search yielded 133 articles. Fourteen articles were analysed to determine the bacterial secretion system and the resistant and virulence of AA. baumannii.


Conclusions: Systems of bacterial type IV secretion present in A. baumannii are crucial in understanding the patterns of virulence and resistance.


Key words: Pathogenicity, type four secretion system (T4SS), A. baumannii, virulence factors, multidrug bacterial resistance (MDR), horizontal gene transfer (HGT).

Andrés Zúñiga-Bahamon, Pontificia Universidad Javeriana. Cali, Colombia.

Grupo de Investigación en Ciencias Básicas y Clínicas, Departamento de Ciencias Básicas de la Salud.

Fabián Tobar, Pontificia Universidad Javeriana. Cali, Colombia.

Grupo de Investigación en Ciencias Básicas y Clínicas, Departamento de Ciencias Básicas de la Salud.

Juan Fernando Duque, Universidad del Valle. Cali, Colombia.

Grupo de Investigación en Biología Integrativa, Facultad de Salud.

Pedro Moreno, Universidad del Valle. Cali, Colombia.

Grupo de Investigación en Bioinformática, Facultad de Ingeniería

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