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In this work, Fibroblast Cells from healthy human gingiva were cultivatedin Vitro and its sensivity to Herpes Simplex Virus 1, (HSVI) was studied. The Fibr0blast were sensitive to HSV l infection using viral stockreference and salivafrom patients with acute symtoms of infection by HSV 1. These cells supporterl viral m ultiplication as evidenced by the develop of cytophatogenic effect and positive immunofluorescence staining with monoclonal and policlonal antibodies against HSV 1. The Gingival Fibroblast might serve as a primary site for viral multiplication in Vivo such as facilitate the access to gingival conective tissue and could serve as a extraneural reservoir for Herpes Simplex Type l.

Adolfo Contreras R., Universidad del Valle. Cali, Colombia

Profesora. Departamento de Estomatología.

Beatriz Parra P., Universidad del Valle. Cali, Colombia.

Bacteriologa MSc.

Contreras R., A., & Parra P., B. (1994). Sensibilidad de fibroblastos gingivales humanos a la infección por herpes simple tipo I (in vitro). Revista Estomatología, 4(1). https://doi.org/10.25100/re.v4i1.5435